Highlights•The antimalarial pipeline has been enriched with new molecules and
targets.•The antimalarial target compound and product profiles have been redefined.•In
addition to treating patients, chemoprevention and blocking transmission have increed
focus.•Because of the dynamics of resistance,(re-) combining existing drugs is
important.Over the past decade, new high-throughput phenotypic assays with malaria
parasites have been developed, and these were used to screen millions of compounds. This …