The perinexus: a new feature of Cx43 gap junction organization

JM Rhett, RG Gourdie - Heart rhythm, 2012 - heartrhythmjournal.com
The origin of present understanding of the structure of GJs comes largely from the electron
microscope (EM). Tangential sections through lanthanum-traced GJs in the EM gave the first
hints of the channel array. 2 Freeze fracture EM provided higher spatial resolution views of
GJs. 3 Aggregates of particles within GJs thought to represent individual connexons were
revealed by freeze fracture to cluster in