[HTML][HTML] Treatment of alopecia areata with simvastatin/ezetimibe
J Cervantes, JJ Jimenez, GM DelCanto… - Journal of Investigative …, 2018 - Elsevier
J Cervantes, JJ Jimenez, GM DelCanto, A Tosti
Journal of Investigative Dermatology Symposium Proceedings, 2018•ElsevierAlopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates
around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic
agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data
indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal
studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in
AA-affected mice.
around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic
agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data
indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal
studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in
AA-affected mice.
Alopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in AA-affected mice.
Elsevier