Sprouty-Related Ena/Vasodilator-Stimulated Phosphoprotein Homology 1-Domain–Containing Protein-2 Critically Regulates Influenza A Virus–Induced Pneumonia
T Ito, J Itakura, S Takahashi, M Sato, M Mino… - Critical care …, 2016 - journals.lww.com
Objectives: Influenza A virus causes acute respiratory infections that induce annual
epidemics and occasional pandemics. Although a number of studies indicated that the virus-
induced intracellular signaling events are important in combating influenza virus infection,
the mechanism how specific molecule plays a critical role among various intracellular
signaling events remains unknown. Raf/MEK/extracellular signal-regulated kinase cascade
is one of the key signaling pathways during influenza virus infection, and the Sprouty-related …
epidemics and occasional pandemics. Although a number of studies indicated that the virus-
induced intracellular signaling events are important in combating influenza virus infection,
the mechanism how specific molecule plays a critical role among various intracellular
signaling events remains unknown. Raf/MEK/extracellular signal-regulated kinase cascade
is one of the key signaling pathways during influenza virus infection, and the Sprouty-related …