Fibroblast growth factor 23: a possible cause of left ventricular hypertrophy in hemodialysis patients

HJ Hsu, MS Wu - The American journal of the medical sciences, 2009 - Elsevier
Background Left ventricular hypertrophy (LVH) is a common cardiovascular disorder and an
independent risk factor for cardiovascular death in dialysis patients. Hyperphosphatemia is
associated with LVH. Previous studies have shown that fibroblast growth factor 23 (FGF23),
which has an important role in phosphate metabolism, is elevated in chronic hemodialysis
patients. Objectives The aim of this study is to determine the association of FGF23 and LVH
and the prognostic value of FGF23 in chronic hemodialysis patients. Materials and Methods …