Developmental expression of thyroid hormone receptor β2 protein in cone photoreceptors in the mouse
L Ng, M Ma, T Curran, D Forrest - Neuroreport, 2009 - journals.lww.com
Thyroid hormone receptor β2 (TRβ2) controls the patterning of cone opsin photopigments
that mediate colour vision. We raised an antiserum against TRβ2 to study cone
photoreceptor development by western blot and immunostaining analyses. TRβ2-positive
cells first appeared between embryonic day 10 (E10) and E12. Numbers increased until
near birth, correlating with generation of the cone population. At birth, signals decreased
until postnatal day 10, then declined to very low levels in adulthood. TRβ2-positive cells …
that mediate colour vision. We raised an antiserum against TRβ2 to study cone
photoreceptor development by western blot and immunostaining analyses. TRβ2-positive
cells first appeared between embryonic day 10 (E10) and E12. Numbers increased until
near birth, correlating with generation of the cone population. At birth, signals decreased
until postnatal day 10, then declined to very low levels in adulthood. TRβ2-positive cells …