The neural basis of atrial fibrillation

BJ Scherlag, E Patterson, SS Po - Journal of electrocardiology, 2006 - Elsevier
This review addresses recent basic and clinical studies which suggest that targeting
autonomic nerves and ganglia on the heart can result in suppression of atrial fibrillation (AF)
with less damage to myocardium than the presently employed procedure which involves
extensive pulmonary vein (PV) isolation from the rest of the left atrium. CLINICAL STUDIES:
Clinical electrophysiologists in 1998 discovered that the majority of patients with paroxysmal
form of AF, resistant to drugs and cardioversion, had focal, ectopic firing arising from the …