Acute myocardial infarction induces bilateral stellate ganglia neural remodeling in rabbits
BL Nguyen, H Li, MC Fishbein, SF Lin, C Gaudio… - Cardiovascular …, 2012 - Elsevier
INTRODUCTION: Myocardial infarction (MI) results in cardiac nerve sprouting in the
myocardium. Whether or not similar neural remodeling occurs in the stellate ganglia (SGs) is
unknown. We aimed to test the hypothesis that MI induces bilateral SG nerve sprouting.
METHODS: Acute MI was created by coronary artery ligation in rabbits (n= 12). Serum nerve
growth factor (NGF) level was measured by enzyme-linked immunosorbent assay. The
hearts and bilateral SGs were harvested for immunohistochemistry after 1 week in six rabbits …
myocardium. Whether or not similar neural remodeling occurs in the stellate ganglia (SGs) is
unknown. We aimed to test the hypothesis that MI induces bilateral SG nerve sprouting.
METHODS: Acute MI was created by coronary artery ligation in rabbits (n= 12). Serum nerve
growth factor (NGF) level was measured by enzyme-linked immunosorbent assay. The
hearts and bilateral SGs were harvested for immunohistochemistry after 1 week in six rabbits …
