Patterning and development of the atrioventricular canal in zebrafish
DS Peal, SN Lynch, DJ Milan - Journal of cardiovascular translational …, 2011 - Springer
DS Peal, SN Lynch, DJ Milan
Journal of cardiovascular translational research, 2011•SpringerProper atrioventricular canal (AVC) patterning and subsequent valvulogenesis is a complex
process, and defects can result in disease or early death. The zebrafish Danio rerio has
become a useful model system for studying AVC development, and much progress has
been made in dissecting out the critical steps. Here, we review the recent advances in the
field and highlight the cellular and molecular changes observed during zebrafish AVC
development.
process, and defects can result in disease or early death. The zebrafish Danio rerio has
become a useful model system for studying AVC development, and much progress has
been made in dissecting out the critical steps. Here, we review the recent advances in the
field and highlight the cellular and molecular changes observed during zebrafish AVC
development.
Abstract
Proper atrioventricular canal (AVC) patterning and subsequent valvulogenesis is a complex process, and defects can result in disease or early death. The zebrafish Danio rerio has become a useful model system for studying AVC development, and much progress has been made in dissecting out the critical steps. Here, we review the recent advances in the field and highlight the cellular and molecular changes observed during zebrafish AVC development.
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