De-novo donor-specific anti-HLA antibodies 30 days after lung transplantation are associated with a worse outcome

J Le Pavec, C Suberbielle, L Lamrani, S Feuillet… - The Journal of Heart and …, 2016 - Elsevier
Background The impact of de-novo donor-specific anti-HLA antibodies (DSA) on patient and
graft survival after lung transplantation remains controversial. We analyzed DSA that
developed at Day 7 and Month (M) 1, M3, M6 and M12 after lung transplantation and
evaluated their impact on chronic lung allograft dysfunction (CLAD) development and
survival. Methods One hundred thirty-four patients who underwent lung transplantation at
our institution between November 2007 and August 2013 were included in this study. During …