Microvascular permeability after an acute and chronic salt load in healthy subjects: a randomized open-label crossover intervention study
NMG Rorije, RHG Olde Engberink, Y Chahid… - …, 2018 - pubs.asahq.org
Background Sodium-induced microcirculatory changes, endothelial surface layer alterations
in particular, may play an important role in sodium-mediated blood pressure elevation.
However, effects of acute and chronic sodium loading on the endothelial surface layer and
microcirculation in humans have not been established. The objective of this study was to
assess sodium-induced changes in blood pressure and body weight as primary outcomes
and also in microvascular permeability, sublingual microcirculatory dimensions, and urinary …
in particular, may play an important role in sodium-mediated blood pressure elevation.
However, effects of acute and chronic sodium loading on the endothelial surface layer and
microcirculation in humans have not been established. The objective of this study was to
assess sodium-induced changes in blood pressure and body weight as primary outcomes
and also in microvascular permeability, sublingual microcirculatory dimensions, and urinary …