Randomized controlled trials often suffer from two major complications, ie, noncompliance
and missing outcomes. One potential solution to this problem is a statistical concept called
intention-to-treat (ITT) analysis. ITT analysis includes every subject who is randomized
according to randomized treatment assignment. It ignores noncompliance, protocol
deviations, withdrawal, and anything that happens after randomization. ITT analysis
maintains prognostic balance generated from the original random treatment allocation. In …