The antinociceptive effects of intracerebroventricular administration of Chicago sky blue 6B, a vesicular glutamate transporter inhibitor
G Yu, S Yi, M Wang, H Yan, L Yan, R Su… - Behavioural …, 2013 - journals.lww.com
Accumulating evidence suggests that vesicular glutamate transporters (VGLUTs), which
control the storage and release of glutamate, may play a role in pain processing. Chicago
sky blue 6B (CSB6B), which is structurally related to glutamate, is a competitive VGLUT
inhibitor without affecting plasma membrane transporters. The present study was designed
to investigate the antinociceptive effects of CSB6B in a number of pain models. The hot-plate
test was used as an acute thermal pain test. Inflammatory pain was evaluated using acetic …
control the storage and release of glutamate, may play a role in pain processing. Chicago
sky blue 6B (CSB6B), which is structurally related to glutamate, is a competitive VGLUT
inhibitor without affecting plasma membrane transporters. The present study was designed
to investigate the antinociceptive effects of CSB6B in a number of pain models. The hot-plate
test was used as an acute thermal pain test. Inflammatory pain was evaluated using acetic …