Endoscopic retrograde cholangio pancreatography (ERCP) combines endoscopic and radiographic techniques and is carried out to allow detailed examination of the bile ducts, pancreatic duct and gallbladder. It can serve as a diagnostic or therapeutic tool. This article provides an update on the procedure as well as indications and contraindications. The nurse's role in caring for patients undergoing ERCP--which includes preparing them for the procedure, observing them post-ERCP and providing health education for discharge and beyond--is also covered.