Lipidomics and biomarker discovery in kidney disease

F Afshinnia, TM Rajendiran, S Wernisch, T Soni… - Seminars in …, 2018 - Elsevier
Technological advances in mass spectrometry–based lipidomic platforms have provided the
opportunity for comprehensive profiling of lipids in biological samples and shown alterations
in the lipidome that occur in metabolic disorders. A lipidomic approach serves as a powerful
tool for biomarker discovery and gaining insight to molecular mechanisms of disease,
especially when integrated with other-omics platforms (ie, transcriptomics, proteomics, and
metabolomics) in the context of systems biology. In this review, we describe the workflow …