Structural predictors of loss of renal function in American Indians with type 2 diabetes
GD Fufaa, EJ Weil, KV Lemley… - Clinical Journal of the …, 2016 - journals.lww.com
Results Of 111 participants (82% women; baseline mean [±SD] age, 46 years old [±10];
diabetes duration, 16 years [±6]; hemoglobin A1c= 9.4%[±2.2]; GFR= 147 ml/min [±56];
median albumin-to-creatinine ratio, 41 mg/g [interquartile range, 13–158]), 51 (46%)
developed renal function loss during a median follow-up of 6.6 years (interquartile range,
3.1–9.0). Fourteen had baseline GFR< 90 ml/min, and three had baseline GFR< 60 ml/min.
Higher mesangial fractional volume (HR, 2.27; 95% confidence interval [95% CI], 1.58 to …
diabetes duration, 16 years [±6]; hemoglobin A1c= 9.4%[±2.2]; GFR= 147 ml/min [±56];
median albumin-to-creatinine ratio, 41 mg/g [interquartile range, 13–158]), 51 (46%)
developed renal function loss during a median follow-up of 6.6 years (interquartile range,
3.1–9.0). Fourteen had baseline GFR< 90 ml/min, and three had baseline GFR< 60 ml/min.
Higher mesangial fractional volume (HR, 2.27; 95% confidence interval [95% CI], 1.58 to …