Acute kidney injury (AKI) is an increasingly common complication of hospitalization and
acute illness. Experimental data indicate that AKI may cause permanent kidney damage
through tubulointerstitial fibrosis and progressive nephron loss, while also lowering the
threshold for subsequent injury. Furthermore, preclinical data suggest that AKI may also
cause distant organ dysfunction. The extension of these findings to human studies suggests
long-term consequences of AKI including, but not limited to recurrent AKI, progressive …