Epileptiform activity induced by lowering extracellular [Mg2+] in combined hippocampal-entorhinal cortex slices: modulation by receptors for norepinephrine and N …

PK Stanton, RSG Jones, I Mody, U Heinemann - Epilepsy research, 1987 - Elsevier
Reduction of extracellular Mg 2+ concentration induced spontaneous and evoked
epileptiform activity in the entorhinal cortex (EC) and dentate gyrus (DG) of combined
hippocampus (HC)-EC slices. Extracellular field potentials, as well as changes in
extracellular Ca 2+ and K+ concentrations, were measured in EC and DG with ion-
selective/reference electrodes during both repetitive and single stimuli. In the EC, lowering
extracellular [Mg 2+] induces both spontaneous and single stimulus evoked ictal events …