Duplication within the haptoglobin Hp2 gene
N Maeda, F Yang, DR Barnett, BH Bowman, O Smithies - Nature, 1984 - nature.com
N Maeda, F Yang, DR Barnett, BH Bowman, O Smithies
Nature, 1984•nature.comDuplication within the haptoglobin Hp2 gene Page 1 © Nature Publishing Group 1984 ~N~ATU~R~E~V~O~L~.~30~9_I~O~M~A~Y~19~8~4
_________________________ ARTICLES~----------------------------------------~1~31 ability to
express receptors for BRF/BCGF upon interaction with antigen and la-restricted T-helper
cells. We thank Drs James N. Ihle, John Garland, Tomas Leanderson, Fritz Melchers,
Norman Iscove and Carolyn Roitsch for the gift of cytokines; Drs Werner Haas, Fritz
Melchers and Stephen Fazekas de St. Groth for critical reading Received 28 October 1983; …
_________________________ ARTICLES~----------------------------------------~1~31 ability to
express receptors for BRF/BCGF upon interaction with antigen and la-restricted T-helper
cells. We thank Drs James N. Ihle, John Garland, Tomas Leanderson, Fritz Melchers,
Norman Iscove and Carolyn Roitsch for the gift of cytokines; Drs Werner Haas, Fritz
Melchers and Stephen Fazekas de St. Groth for critical reading Received 28 October 1983; …
Abstract
DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1genes, probably in an Hp1F/Hp1S heterozygote.
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