Sepsis and endothelial permeability

WL Lee, AS Slutsky - New England Journal of Medicine, 2010 - Mass Medical Soc
New England Journal of Medicine, 2010Mass Medical Soc
Sepsis and Endothelial Permeability Page 1 n engl j med 363;7 nejm.org august 12, 2010
689 clinical implications of basic research The new england journal of medicine Sepsis and
Endothelial Permeability Warren L. Lee, MD, Ph.D., and Arthur S. Slutsky, MD Sepsis,
derived from the Greek verb sepo (meaning “I rot”), has been recognized for millennia and
refers to the disseminated inflammatory response elicited by microbial infections. Despite its
ancient etymology, sepsis remains a current challenge: it is increasing in frequency …
Molecular dissection in three models of sepsis implicates a signaling pathway in maintaining adhesion of endothelial cells to protect against vascular leak.
The New England Journal Of Medicine