It is known that deformation of red blood cells (RBCs) is linked to ATP release from the cells.
Further, membrane cholesterol has been shown to alter properties of the cell membrane
such as fluidity and bending stiffness. Membrane cholesterol content is increased in some
cardiovascular diseases, for example, in individuals with acute coronary syndromes and
chronic stable angina, and therefore, because of the potential clinical relevance, we
investigated the influence of altered RBC membrane cholesterol levels on ATP release …