Comparison of the effects of rosuvastatin monotherapy and atorvastatin-ezetimibe combined therapy on the structure of erythrocyte membranes in patients with …

M Olszewska-Banaszczyk, P Jackowska… - Pharmacological …, 2018 - Elsevier
Background Abnormalities in the physical properties of the red blood cells (RBCs)
membranes may underlie the defects that are strongly linked to cardiovascular diseases
(CVD). The aim of the study was to compare the effects of two therapies of equal hipolipemic
efficacy on the erythrocyte membrane fluidity, concentration of membrane cholesterol, lipids
peroxidation and RBCs distribution witdh in patients with CVD. Methods The study included
44 patients with angiographic evidence of CVD, who despite previous 6-month hypolipemic …