Physiologic variables affecting thromboxane B2 production in human whole blood

P Alessandrini, P Avogaro, GB Bon, P Patrignani… - Thrombosis research, 1985 - Elsevier
Thrombin-induced thromboxane (TX) A 2 production in whole blood, as reflected by serum
TXB 2 measurements, has proven to be a simple and reproducible capacity-related index of
platelet TXA 2 production ex vivo. In the present study we have determined the influence of a
number of physiologic variables on serum TXB 2 measurements performed by
radioimmunoassay in a group of 177 subjects undergoing evaluation for atherosclerosis risk
factors. Serum TXB 2 averaged 300±108 ng/ml in the whole group, with a normal …