Acute myocardial infarction: measurement of arachidonate end-products in whole blood as an index of platelet cyclo-oxygenase activity in vivo
D Rousson, M Lagarde, P Touboul, M Dechavanne - Thrombosis research, 1987 - Elsevier
The endogenous arachidonic acid metabolism was investigated ex vivo, in separated serum
from clotted whole blood, soon after the onset of acute myocardial infarction (3.3±0.7 hr). A
group of eight consecutive male patients was selected, since no evidence was obtained of
any associated disease known to increase platelet activity or any recent exposure to cyclo-
oxygenase inhibitors. This group of patients compared to an age and sex matched control
group showed a large decrease in the platelet cyclo-oxygenase end-products in whole …
from clotted whole blood, soon after the onset of acute myocardial infarction (3.3±0.7 hr). A
group of eight consecutive male patients was selected, since no evidence was obtained of
any associated disease known to increase platelet activity or any recent exposure to cyclo-
oxygenase inhibitors. This group of patients compared to an age and sex matched control
group showed a large decrease in the platelet cyclo-oxygenase end-products in whole …