Abstract Type 2 diabetes (T2D) is one of the major risk factors for tuberculosis (TB). In this
study, a diet induced murine model of T2D (DIMT2D) was developed and characterized in
the context of metabolic, biochemical and histopathological features following diet
intervention. Mycobacterial susceptibility was investigated using Mycobacterium fortuitum as
a surrogate. Phagocytic capability of alveolar macrophages and resident peritoneal
macrophages were determined by in vitro assays using mycolic acid coated beads and M …