Irritable bowel syndrome: a clinical review

WD Chey, J Kurlander, S Eswaran - Jama, 2015 - jamanetwork.com
Importance Irritable bowel syndrome (IBS) affects 7% to 21% of the general population. It is
a chronic condition that can substantially reduce quality of life and work productivity.
Objectives To summarize the existing evidence on epidemiology, pathophysiology, and
diagnosis of IBS and to provide practical treatment recommendations for generalists and
specialists according to the best available evidence. Evidence Review A search of Ovid
(MEDLINE) and Cochrane Database of Systematic Reviews was performed for literature …