Human umbilical cord mesenchymal stem cells derived from Wharton's jelly differentiate into insulin-producing cellsin vitro
H Wang, L Lin, H He, YOU Fang, WZ Li… - Chinese medical …, 2011 - journals.lww.com
Background Islet transplantation is an effective way of reversing type I diabetes. However,
islet transplantation is hampered by issues such as immune rejection and shortage of donor
islets. Mesenchymal stem cells can differentiate into insulin-producing cells. However, the
potential of human umbilical cord mesenchymal stem cells (huMSCs) to become insulin-
producing cells remains undetermined. Methods We isolated and induced cultured huMSCs
under islet cell culture conditions. The response of huMSCs were monitored under an …
islet transplantation is hampered by issues such as immune rejection and shortage of donor
islets. Mesenchymal stem cells can differentiate into insulin-producing cells. However, the
potential of human umbilical cord mesenchymal stem cells (huMSCs) to become insulin-
producing cells remains undetermined. Methods We isolated and induced cultured huMSCs
under islet cell culture conditions. The response of huMSCs were monitored under an …