A quantitative comparison of antibodies to programmed cell death 1 ligand 1
Importance Assessment of PD-L1 (programmed cell death 1 ligand 1) expression by
immunohistochemical analysis has been used as a predictive diagnostic test to identify
responders and guide treatment in trials of the PD-1 (programmed cell death 1) axis
inhibitors. The definition of PD-L1 positive lacks standardization, and prediction of response
by immunohistochemical analysis is additionally limited by the subjective nature of this
technique. Objective To examine whether PD-L1 antibody reagents are interchangeable by …
immunohistochemical analysis has been used as a predictive diagnostic test to identify
responders and guide treatment in trials of the PD-1 (programmed cell death 1) axis
inhibitors. The definition of PD-L1 positive lacks standardization, and prediction of response
by immunohistochemical analysis is additionally limited by the subjective nature of this
technique. Objective To examine whether PD-L1 antibody reagents are interchangeable by …