Significantly altered expression of miR-511-3p and its target AKT3 has negative prognostic value in human prostate cancer
F Zhang, Z Wu - Biochimie, 2017 - Elsevier
Purpose In this study, we assessed the expression and functions of microRNA-511-3p (miR-
511-3p) in human prostate cancer (CaP). Methods Gene expressions of miR-511-3p in CaP
cells and human CaP tumors were assessed by qPCR. In VCaP and PC3 cells, miR-511-3p
was overexpressed by lentivirus. The functions of miR-511-3p upregulation in regulating in
vitro cancer proliferation, migration and in vivo cancer growth were assessed by MTT,
transwell and transplantation assays, respectively. Downstream target gene of miR-511-3p …
511-3p) in human prostate cancer (CaP). Methods Gene expressions of miR-511-3p in CaP
cells and human CaP tumors were assessed by qPCR. In VCaP and PC3 cells, miR-511-3p
was overexpressed by lentivirus. The functions of miR-511-3p upregulation in regulating in
vitro cancer proliferation, migration and in vivo cancer growth were assessed by MTT,
transwell and transplantation assays, respectively. Downstream target gene of miR-511-3p …
