Purpose While androgen deprivation therapy can delay cancer progression and reduce
tumor burden, its use can be limited by adverse side effects. We evaluated the effect of
androgen deprivation therapy on mental and emotional well-being in men with
nonmetastatic prostate cancer. Materials and Methods Participants were enrolled in the
national CaPSURE (Cancer of the Prostate Strategic Urologic Research Endeavor) registry,
and treated with radical prostatectomy, external beam radiation therapy or brachytherapy …