Graftskin therapy in epidermolysis bullosa
DP Fivenson, L Scherschun, M Choucair… - Journal of the American …, 2003 - Elsevier
Background: Epidermolysis bullosa (EB) is a family of 23 genetic skin disorders for which
treatments are mainly supportive. Graftskin is a bilayered living human skin construct
characterized by a normal expression profile of all the genes reported as mutant in EB.
Objective: The objective of this study was to evaluate the efficiency and durability of graftskin
in the treatment of EB. Methods: A total of 9 children with EB were treated with graftskin.
These include EB simplex: Dowling-Meara type (n= 2); Weber-Cockayne type (n= 1); …
treatments are mainly supportive. Graftskin is a bilayered living human skin construct
characterized by a normal expression profile of all the genes reported as mutant in EB.
Objective: The objective of this study was to evaluate the efficiency and durability of graftskin
in the treatment of EB. Methods: A total of 9 children with EB were treated with graftskin.
These include EB simplex: Dowling-Meara type (n= 2); Weber-Cockayne type (n= 1); …