Expression of mast cell–associated genes is upregulated in adult eosinophilic esophagitis and responds to steroid or dietary therapy
KSH Blatman, N Gonsalves, I Hirano… - Journal of allergy and …, 2011 - jacionline.org
Although the role of eosinophils in EoE is well established, that of mast cells is less clear. 3,
4 In 2001, Straumann et al 5 identified increased mast cell numbers in adults with EoE. 5
However, despite much discussion, the roles for mast cells in patients with EoE have not
been defined. 4 Recently, studies by Abonia et al 6 and Aceves et al 7 have defined an
involvement of mast cells in pediatric EoE. We have concurrently been investigating mast
cells in adult EoE. Our results in adults with EoE, described in this article, now support the …
4 In 2001, Straumann et al 5 identified increased mast cell numbers in adults with EoE. 5
However, despite much discussion, the roles for mast cells in patients with EoE have not
been defined. 4 Recently, studies by Abonia et al 6 and Aceves et al 7 have defined an
involvement of mast cells in pediatric EoE. We have concurrently been investigating mast
cells in adult EoE. Our results in adults with EoE, described in this article, now support the …