Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus

CM Boney, A Verma, R Tucker, BR Vohr - Pediatrics, 2005 - publications.aap.org
Objective. Childhood obesity has contributed to an increased incidence of type 2 diabetes
mellitus and metabolic syndrome (MS) among children. Intrauterine exposure to diabetes
and size at birth are risk factors for type 2 diabetes mellitus, but their association with MS in
childhood has not been demonstrated. We examined the development of MS among large-
for-gestational-age (LGA) and appropriate-for-gestational age (AGA) children. Study Design.
The major components of MS (obesity, hypertension, dyslipidemia, and glucose intolerance) …