The morphology and physiology of hair cells in organotypic cultures of the mouse cochlea
IJ Russell, GP Richardson - Hearing research, 1987 - Elsevier
Organotypic explant cultures were prepared from the cochleas of 1 to 3 day post-natal mice
and maintained in vitro for up to 5 days. The hair cells retain morphological integrity for the
duration of the culture period although they exhibit embryological features such as a
kinocilium and additional microvilli on their apical surfaces. The resting membrane
potentials of mouse inner hair cells (IHCs) in vitro are similar to those of guinea-pig IHCs in
vivo but the membrane potentials of outer hair cells (OHCs) in the mouse cochlea in vitro are …
and maintained in vitro for up to 5 days. The hair cells retain morphological integrity for the
duration of the culture period although they exhibit embryological features such as a
kinocilium and additional microvilli on their apical surfaces. The resting membrane
potentials of mouse inner hair cells (IHCs) in vitro are similar to those of guinea-pig IHCs in
vivo but the membrane potentials of outer hair cells (OHCs) in the mouse cochlea in vitro are …