Vascular endothelial growth factor (VEGF)-A: role on cardiac angiogenesis following myocardial infarction
T Zhao, W Zhao, Y Chen, RA Ahokas, Y Sun - Microvascular research, 2010 - Elsevier
The current study is to determine the regulatory role of VEGF-A in cardiac angiogenesis
following myocardial infarction (MI). Cardiac angiogenic response and temporal/spatial
expression of VEGF-A/VEGF receptors (VEGFR) were examined at 1, 2, 6, 12h and 1, 2, 3, 4,
7, 14, and 28days postMI. We found that following MI, newly formed vessels first appeared at
the border zone between noninfarcted and infarcted myocardium as early as day 3 and
subsequently in the infarcted myocardium. Vascular density in the infarcted myocardium …
following myocardial infarction (MI). Cardiac angiogenic response and temporal/spatial
expression of VEGF-A/VEGF receptors (VEGFR) were examined at 1, 2, 6, 12h and 1, 2, 3, 4,
7, 14, and 28days postMI. We found that following MI, newly formed vessels first appeared at
the border zone between noninfarcted and infarcted myocardium as early as day 3 and
subsequently in the infarcted myocardium. Vascular density in the infarcted myocardium …