[HTML][HTML] Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma
SAM Rao, V Santosh, K Somasundaram - Modern Pathology, 2010 - Elsevier
Malignant astrocytoma includes anaplastic astrocytoma (grade III) and glioblastoma (grade
IV). Among them, glioblastoma is the most common primary brain tumor with dismal
responses to all therapeutic modalities. We performed a large-scale, genome-wide
microRNA (miRNA)(n= 756) expression profiling of 26 glioblastoma, 13 anaplastic
astrocytoma and 7 normal brain samples with an aim to find deregulated miRNA in
malignant astrocytoma. We identified several differentially regulated miRNAs between these …
IV). Among them, glioblastoma is the most common primary brain tumor with dismal
responses to all therapeutic modalities. We performed a large-scale, genome-wide
microRNA (miRNA)(n= 756) expression profiling of 26 glioblastoma, 13 anaplastic
astrocytoma and 7 normal brain samples with an aim to find deregulated miRNA in
malignant astrocytoma. We identified several differentially regulated miRNAs between these …