Integrin ligands at a glance

JD Humphries, A Byron… - Journal of cell …, 2006 - journals.biologists.com
Journal of cell science, 2006journals.biologists.com
The poster shows the major integrinligand combinations, using hypothetical cell surfaces.
We have not attempted a comprehensive cataloguing, but instead we have consulted with a
number of colleagues and reached a consensus view on the best-validated integrin ligands.
There are many other ligands for different integrins, the inclusion of which would overly
complicate the poster. By citing the best studied receptor-ligand combinations, we are aware
that some reports and low-affinity interactions (which are nonetheless functionally relevant) …
The poster shows the major integrinligand combinations, using hypothetical cell surfaces. We have not attempted a comprehensive cataloguing, but instead we have consulted with a number of colleagues and reached a consensus view on the best-validated integrin ligands. There are many other ligands for different integrins, the inclusion of which would overly complicate the poster. By citing the best studied receptor-ligand combinations, we are aware that some reports and low-affinity interactions (which are nonetheless functionally relevant) may be discriminated against, and for this we apologise. Some of the interactions that are supported by convincing data are nonetheless included below.
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