Hepatocellular carcinoma is an end-stage complication of non-alcoholic fatty liver disease
(NAFLD). Inflammation plays a critical role in the progression of non-alcoholic fatty liver
disease and the development of hepatocellular carcinoma. However, whether steatosis per
se promotes liver cancer, and the molecular mechanisms that control the progression in this
disease spectrum remain largely elusive. The Janus kinase signal transducers and
activators of transcription (JAK-STAT) pathway mediates signal transduction by numerous …