Despite higher body fat content, Ecuadorian subjects with Laron syndrome have less insulin resistance and lower incidence of diabetes than their relatives
J Guevara-Aguirre, P Procel, C Guevara… - Growth Hormone & IGF …, 2016 - Elsevier
In the present pandemics of obesity and insulin resistant diabetes mellitus (DM), the specific
contribution of etiological factors such as shifts in nutritional and exercise patterns, genetic
and hormonal, is subject of ongoing research. Among the hormonal factors implicated, we
selected obesity-driven insulin resistance for further evaluation. It is known that growth
hormone (GH) has profound effects on carbohydrate metabolism. In consequence, we
compared the effects of the lack of the counter-regulatory effects of GH, in a group of …
contribution of etiological factors such as shifts in nutritional and exercise patterns, genetic
and hormonal, is subject of ongoing research. Among the hormonal factors implicated, we
selected obesity-driven insulin resistance for further evaluation. It is known that growth
hormone (GH) has profound effects on carbohydrate metabolism. In consequence, we
compared the effects of the lack of the counter-regulatory effects of GH, in a group of …