The morphological features of the adult human adrenal cortex are described with particular
respect to changes induced by alterations in function of the hypothalamo-pituitary axis. The
occurrence of nodules in the normal and hyperplastic cortex (Cushing's and Conn's
syndromes) is discussed in relation to the diagnostic problems that they still pose.
Explanations based on the normal mechanisms of functional zonation in the cortex are
provided for the different cell types which comprise cortical neoplasms associated with …