[HTML][HTML] Evaluation of apoptosis in skin biopsies of patients of borderline leprosy and lepra type 1 reaction

N Patnaik, S Agarwal, S Sharma… - Indian Journal of …, 2015 - journals.lww.com
Background: The role of apoptosis is not clear in leprosy and lepra reactions. Objectives: To
evaluate frequency of apoptosis in skin lesions of borderline leprosy and Type 1 lepra
reaction. Methods: Sixty patients with borderline leprosy (30 with clinically diagnosed Type 1
reaction (T1R)(Group I) and 30 without clinical evidence of reaction (Group II)) were
analyzed in this prospective study. Apoptosis was detected by two different methods for
comparison, that is, histopathologic examination (HPE) and deoxyribonucleic acid (DNA) …