[HTML][HTML] Obesity wars: molecular progress confronts an expanding epidemic

JS Flier - Cell, 2004 - cell.com
Cell, 2004cell.com
The worldwide prevalence of obesity is increasing at an alarming rate, with major adverse
consequences for human health. This" obesity epidemic" is paralleled by a rapid and
substantive increase in our understanding of molecular pathways and physiologic systems
underlying the regulation of energy balance. While efforts to address the environmental
factors that are responsible for the recent" epidemic" must continue, new molecular and
physiologic insights into this system offer exciting possibilities for future development of …
Abstract
The worldwide prevalence of obesity is increasing at an alarming rate, with major adverse consequences for human health. This "obesity epidemic" is paralleled by a rapid and substantive increase in our understanding of molecular pathways and physiologic systems underlying the regulation of energy balance. While efforts to address the environmental factors that are responsible for the recent "epidemic" must continue, new molecular and physiologic insights into this system offer exciting possibilities for future development of successful therapies.
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