Involvement of Tsukushi in diverse developmental processes
Tsukushi (TSK) is a small signaling molecule which takes part in different developmental
processes of multiple vertebrate organisms. The diverse activity of TSK depends on its ability
to bind various intermediate molecules from different major signaling pathways. Interactions
of TSK with BMP, FGF, TGF-β and Wnt pathways have already been confirmed. In this
review, we will introduce the latest information regarding the involvement of TSK in
developmental events. We suggest a fine tuning role for TSK in multiple signaling cascades …
processes of multiple vertebrate organisms. The diverse activity of TSK depends on its ability
to bind various intermediate molecules from different major signaling pathways. Interactions
of TSK with BMP, FGF, TGF-β and Wnt pathways have already been confirmed. In this
review, we will introduce the latest information regarding the involvement of TSK in
developmental events. We suggest a fine tuning role for TSK in multiple signaling cascades …
Abstract
Tsukushi (TSK) is a small signaling molecule which takes part in different developmental processes of multiple vertebrate organisms. The diverse activity of TSK depends on its ability to bind various intermediate molecules from different major signaling pathways. Interactions of TSK with BMP, FGF, TGF-β and Wnt pathways have already been confirmed. In this review, we will introduce the latest information regarding the involvement of TSK in developmental events. We suggest a fine tuning role for TSK in multiple signaling cascades. Also, we recommend further studies on the developmental role of TSK to fully reveal its potential.
Springer