The role of hepassocin in the development of non-alcoholic fatty liver disease
HT Wu, FH Lu, HY Ou, YC Su, HC Hung, JS Wu… - Journal of …, 2013 - Elsevier
Background & Aims While non-alcoholic fatty liver disease (NAFLD) is the most common risk
factor of chronic liver disease, the mechanisms that initiate its development are obscure.
Hepassocin (HPS) is a hepatokine that has been reported to be involved in liver
regeneration. In addition to the mitogenic activity of HPS, HPS expression is decreased in
patients with hepatoma. However, the role of HPS in NAFLD is still unknown. Methods A
total of 393 subjects with (n= 194) or without (n= 199) NAFLD were enrolled to evaluate the …
factor of chronic liver disease, the mechanisms that initiate its development are obscure.
Hepassocin (HPS) is a hepatokine that has been reported to be involved in liver
regeneration. In addition to the mitogenic activity of HPS, HPS expression is decreased in
patients with hepatoma. However, the role of HPS in NAFLD is still unknown. Methods A
total of 393 subjects with (n= 194) or without (n= 199) NAFLD were enrolled to evaluate the …