Structural–functional correlates of the 3-dimensional arrangement of the myocytes making up the ventricular walls

RH Anderson, D Sanchez-Quintana, P Niederer… - The Journal of thoracic …, 2008 - jtcvs.org
The aphorism from Mencken, which we have chosen as the header for our review, is
particularly pertinent to the ongoing controversies regarding the anatomic arrangements of
the myocytes that make up the ventricular mass. The 3-dimensional architecture of these
cells has fascinated anatomists for centuries. Despite multiple investigations, it has proved
difficult to relate the presumed anatomic arrangements to function so as to adequately
explain the contractions that produce the forces driving the systemic and pulmonary …