[HTML][HTML] MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development
The epicardium is a sheet of epithelial cells covering the heart during early cardiac
development. In recent years, the epicardium has been identified as an important contributor
to cardiovascular development, and epicardium-derived cells have the potential to
differentiate into multiple cardiac cell lineages. Some epicardium-derived cells that undergo
epithelial-to-mesenchymal transition and delaminate from the surface of the developing
heart subsequently invade the myocardium and differentiate into vascular smooth muscle of …
development. In recent years, the epicardium has been identified as an important contributor
to cardiovascular development, and epicardium-derived cells have the potential to
differentiate into multiple cardiac cell lineages. Some epicardium-derived cells that undergo
epithelial-to-mesenchymal transition and delaminate from the surface of the developing
heart subsequently invade the myocardium and differentiate into vascular smooth muscle of …