[HTML][HTML] The muscle-specific protein phosphatase PP1G/RGL (GM) is essential for activation of glycogen synthase by exercise
WG Aschenbach, Y Suzuki, K Breeden, C Prats… - Journal of Biological …, 2001 - ASBMB
In skeletal muscle both insulin and contractile activity are physiological stimuli for glycogen
synthesis, which is thought to result in part from the dephosphorylation and activation of
glycogen synthase (GS). PP1G/R GL (GM) is a glycogen/sarcoplasmic reticulum-associated
type 1 phosphatase that was originally postulated to mediate insulin control of glycogen
metabolism. However, we recently showed (Suzuki, Y., Lanner, C., Kim, J.-H., Vilardo, PG,
Zhang, H., Jie Yang, J., Cooper, LD, Steele, M., Kennedy, A., Bock, C., Scrimgeour, A …
synthesis, which is thought to result in part from the dephosphorylation and activation of
glycogen synthase (GS). PP1G/R GL (GM) is a glycogen/sarcoplasmic reticulum-associated
type 1 phosphatase that was originally postulated to mediate insulin control of glycogen
metabolism. However, we recently showed (Suzuki, Y., Lanner, C., Kim, J.-H., Vilardo, PG,
Zhang, H., Jie Yang, J., Cooper, LD, Steele, M., Kennedy, A., Bock, C., Scrimgeour, A …