[HTML][HTML] Developing a lower limb lymphedema animal model with combined lymphadenectomy and low-dose radiation
CY Yang, DH Nguyen, CW Wu, YHD Fang… - … Surgery–Global Open, 2014 - journals.lww.com
Background: This study was aimed to establish a consistent lower limb lymphedema animal
model for further investigation of the mechanism and treatment of lymphedema. Methods:
Lymphedema in the lower extremity was created by removing unilateral inguinal lymph
nodes followed by 20, 30, and 40 Gy (groups IA, IB, and IC, respectively) radiation or by
removing both inguinal lymph nodes and popliteal lymph nodes followed by 20 Gy (group II)
radiation in Sprague-Dawley rats (350–400 g). Tc 99 lymphoscintigraphy was used to …
model for further investigation of the mechanism and treatment of lymphedema. Methods:
Lymphedema in the lower extremity was created by removing unilateral inguinal lymph
nodes followed by 20, 30, and 40 Gy (groups IA, IB, and IC, respectively) radiation or by
removing both inguinal lymph nodes and popliteal lymph nodes followed by 20 Gy (group II)
radiation in Sprague-Dawley rats (350–400 g). Tc 99 lymphoscintigraphy was used to …
