Rapid and sequential quantitation of salivary gland-associated mouse cytomegalovirus in oral lavage
Y Kamimura, LL Lanier - Journal of virological methods, 2014 - Elsevier
Cytomegalovirus (CMV) establishes a persistent infection in the salivary glands and
transmits to other hosts. Mouse cytomegalovirus (MCMV) is a well-characterized model for
studying the mechanisms of host responses against CMV. The viral load in salivary glands
has been measured traditionally because it has been considered to reflect the consequence
of anti-virus responses by T cells and natural killer (NK) cells. However, the standard plaque
assay is cumbersome and it is impossible to monitor sequentially the viral load in same host …
transmits to other hosts. Mouse cytomegalovirus (MCMV) is a well-characterized model for
studying the mechanisms of host responses against CMV. The viral load in salivary glands
has been measured traditionally because it has been considered to reflect the consequence
of anti-virus responses by T cells and natural killer (NK) cells. However, the standard plaque
assay is cumbersome and it is impossible to monitor sequentially the viral load in same host …