Effects of oxygen on the development and severity of retinopathy of prematurity

ME Hartnett, RH Lane - Journal of American Association for Pediatric …, 2013 - Elsevier
In 1942, when retinopathy of prematurity (ROP) first manifested as retrolental fibroplasia, the
technology to monitor or regulate oxygen did not exist, and a fundus examination of preterm
infants was not routinely performed. Supplemental, uncontrolled oxygen at birth has since
been found to cause retrolental fibroplasia. At the same time, technological advances have
made it possible to regulate oxygen and detect early forms of ROP. Nevertheless, despite
our better understanding of ROP and ongoing investigations of supplemental therapeutic …